Date:9 th June 2000
Venue: Lecture Theatre 2, Academic Avenue, The John Radcliffe Hospital, Oxford
Acid Fast Club
Scientific Programme
Session 1
1. A mechanism for CD8+ T cell mediated suppression of intracellular mycobacterial growth.R Brookes, H McShane, N Goonetilleke, A Lalvani, AA Psthan, DA Price, GM Griffiths & A Hill. Oxford University.2. OmpATb – a pore-forming protein of M. tuberculosis and how it may be regulated.R Speight & P Draper. NIMR.3. An increase in expression of a M. tuberculosis mycolyl transferase gene (fbpB) occurs early after infection of human monocytes.RJ Wilkinson123, LE DesJardin2, BM Gibson2, KA Wilkinson1, D Poleman1, RA Kanost1, KD Eisenach2, Z Toossi2. 1Division of Infectious Diseases, Case Western Reseve University, Cleveland, Medical Research Service. 2JL McClellan Memorial Veterans’ Administration Hospital, Little Rock. 3Wellcome Centre for Clinical Tropical Medicine, Imperial College of Medicine, Northwick Park Hospital.4. Genetic Transformation of Mycobacterium paratuberculosis.S Thorne & JJ McFadden. University of Surrey.5. Role of heat shock proteins in inflammation: M. tuberculosis chaperonin 60.1 (hsp 60) is a more potent cytokine-stimulator than chaperonin 60.2 (hsp 65) and contains a cryptic CD14-binding domain.JC Lewthwaite, ARM Coates, S Kahn, M Singh, P Mascagni, S Poole, M Roberts & B Henderson. Eastman Dental Institute and St George’s Hospital Medical School.6. The use of recombinant viruses as tuberculosis vaccines.N Goonetilleke, R Anderson, H McShane, S Gilbert, R Brookes & A Hill. Oxford University.Session 2 7. Crystal Structure of Mycobacterium tuberculosis Chaperonin 10.
M Roberts, AR Coker, ARM Coates and SP Wood. St George’s Hopsital Medical School and Southampton University.8. Growth control and dormancy in Mycobacterium smegmatis.R Wright, J Dickinson, S Thorne, M Bushell & JJ McFadden. University of Surrey9. Protection against tuberculosis in a prime-boost regime is mediated by one CD4+ and one CD8+ T cell epitope.H McShane, S Behboudi, N Goonetilleke, S Gilbert, R Brookes & A Hill. Oxford University.
10. Comparative studies of defined skin test antigens in M. bovis infected guinea pigs and cattle.AO Whelan, HM Vordermeier & RG Hewinson. VLA Weybridge.11. Stressed up, Messed up: De-regulation of HSP70 response in Mcobacterium tuberculosis.G Stewart, V Snewin, P Tormay, P O’Goara, M Goyal, I Brown & DB Young. Imperial College of Medicine at St Mary’s Hospital.