Scientific Sessions

January 2003 Meeting

Session 1

1. Satya Das, KE Britton, DW Wareham (introduced by Tanya Parish). TB imaging- a new way forward?.

2. Gretta Roberts, Debbie Smith, Jo Betts, Neil Stoker, Tanya Parish. The SenX3 RegX3 two component regulatory system of Mycobacterium tuberculosis.

3. Helen Fletcher, Roger Brookes, Patrick Owiafe, Philip Hill, Mark Doherty, Graham Rook, Alimuddin Zumla & the VACSEL study group. Increased mRNA encoding IL-42 and IL-4 in  unstimulated peripheral blood mononuclear cells from those TB contacts whose cells release IFN in response to ESAT-6.

4. Lisa Rickman, Jeffrey Green, Colin Scott, Jo Colston and Roger Buxton. The cAMP receptor protein (CRP) of Mycobacterium tuberculosis: effect of a null mutation in this global regulator.

5. Rosemary Weir, Paul Fine,  Bernadette Nazareth, Sian Floyd,  Gillian  Black,  Carolynne Stanley,  Lyn Bliss,  Keith Branson,  and Hazel M. Dockrell. Naturally acquired sensitivity to PPDs of environmental mycobacteria among UK school children.

6. John L Stanford and Helen D Donoghue on behalf of the Nicaragua Study Group Leprosy in Nicaragua. Is there a major endemic of tuberculoid leprosy in Cental America?

Session 2

7. Paul Wheeler, Lisa Keating, Esen Wooff, Steve Gordon, Tanya Parish and Glyn Hewinson. What pathogenic mycobacteria want- amino acid biosynthesis and availability in the host.

8. K. G. Papavinasasundaram, Bosco H. Y. Chan, Elaine O. Davis and M. Joseph Colston. Roles of Serine/Threonine protein kinases in M. tuberculosis athogenicity.

9. L. Rosa Brunet, C. Zuany-Amorim,  E. Sawicka, C. Manlius, A. Le Moine,  V. Adams, B. Palmer, J. Hunt, G.S. Besra, C. Walker, G. Rook. Induction by Mycobacterium vaccae and its components of regulatory mechanisms involving IL-10 and TGF-β that suppress allergic responses.

10. Yanmin Hu, Sharon Kendall, Neil Stoker, Anthony Coates. Mycobacterium tuberculosis sigJ knockout alters sensitivity of slow- growing bacteria to hydrogen peroxide.

11. Kazi F, Prakash M, Ewer K, Waller S, Varia H, Pasvol G & Lalvani A. Effector memory CD8 T cells are associated with long-term immune control of M. tuberculosis.

12. Taylor GM, Stewart GR, Cooke M, Ladva, S, Young DB. Koch’s Bacillus – A look at the first isolate of M. tuberculosis from a modern perspective.